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US 12,614,620 B2Granted
Biological function estimation device and biological function estimation method
AssigneeTerumo Kabushiki Kaisha
InventorsKei Honda, Yoshihito Machida
Life of this patent
Estimating the term…
Abstract
A biological function estimation device includes a processor configured to predict a drug reaction in a patient based on an evaluation value obtained by evaluating a biological function of the patient from a test result before drug administration and data on a drug to be administered to the patient, and configured to correct the evaluation value according to a comparison result between an obtained prediction value and a measurement value obtained by measuring the drug reaction after the drug administration.
Claims19
A biological function estimation system comprising:
- a biological function estimation device comprising a processor;
- a pump;
- the processor configured to:
- predict a drug reaction before a drug administration in a patient based on an evaluation value of a biological function obtained by evaluating the biological function of the patient from a test result before the drug administration and data on a drug to be administered to the patient, the drug reaction being urine volume per unit of time as measured by a urine volume sensor and the evaluation value is a value obtained by evaluating a renal function as the biological function;
- and
- correct the evaluation value according to a comparison result between an obtained prediction value, which is related to the drug reaction and different from the evaluation value, and a measurement value, which is related to the drug reaction and different from the evaluation value, obtained by measuring the drug reaction after the drug administration,
- wherein for drug administration at each of a plurality of time points, the processor is configured to:
- set a drug administration pattern at each of the plurality of time points;
- predict the drug reaction based on a corrected value of the evaluation value obtained for drug administration at any one of the plurality of time points and data on the drug to be administered to the patient at a next time point;
- correct the corrected value of the evaluation value related to the drug reaction according to a comparison result between an obtained new prediction value and a new measurement value obtained by measuring the drug reaction after the drug administration at the next time point;
- adjust, according to a comparison result between the new prediction value and the new measurement value obtained for drug administration, the drug administration pattern at a new next time point;
- and
- control the pump by setting at least one of the number of times of administration of the drug and an administration amount per unit time of the drug so as to administrate the drug according to an adjusted drug administration pattern at the new next time point;
- and
- wherein the pump administers the drug in accordance with the adjusted drug administration pattern.
12 more elements
A biological function estimation method comprising:
- predicting, by a processor, a drug reaction before drug administration in a patient based on an evaluation value of a biological function, which is obtained by evaluating a biological function of the patient from a test result before the drug administration and data on a drug to be administered to the patient to obtain a prediction value that is related to the drug reaction and different from the evaluation value, the drug reaction being urine volume per unit of time as measured by a urine volume sensor and the evaluation value is a value obtained by evaluating a renal function as the biological function;
- administering the drug to the patient by a pump;
- measuring, by the urine volume sensor, a urine volume per unit of time after the drug administration to obtain a measurement value that is related to the drug reaction and different from the evaluation value;
- correcting, by the processor, the evaluation value according to a comparison result between an obtained prediction value and an obtained measurement value;
- setting a drug administration pattern at each of the plurality of time points;
- predicting the drug reaction based on a corrected value of the evaluation value obtained for drug administration at any one of the plurality of time points and data on the drug to be administered to the patient at a next time point;
- correcting the corrected value of the evaluation value related to the drug reaction according to a comparison result between an obtained new prediction value and a new measurement value obtained by measuring the drug reaction after the drug administration at the next time point;
- adjusting, according to a comparison result between the new prediction value and the new measurement value obtained for drug administration, the drug administration pattern at a new next time point;
- controlling the pump by setting at least one of the number of times of administration of the drug and an administration amount per unit time of the drug so as to administrate the drug according to an adjusted drug administration pattern at the new next time point;
- and
- administering the drug to the patient in accordance with the adjusted drug administration pattern by the pump.
8 more elements
Dependencies are inferred from the claim text.