Peak area display device, peak area display method, peak area calculation device and peak area calculation method

A peak area calculation device comprising:

• an acquirer that acquires measurement data measured by a chromatograph;
• and
• a peak area calculator that fits a model function to a chromatogram to obtain a maximum value or a minimum value of a peak area by performing optimization calculation to maximize or minimize the peak area calculated based on the model function while keeping a value to be taken by a loss function representing a residual between the chromatogram obtained from the measurement data and the model function in a predetermined range,
• wherein the peak area calculator is configured to:
• calculate a minimum loss value representing the residual between the chromatogram and the model function,
• set a predetermined range between the minimum loss value and a value obtained by adding a predetermined value to the minimum loss value, and
• calculate the maximum value or the minimum value of the peak area by varying a parameter of the model function under a constraint condition that the residual between the chromatogram and the model function is within the predetermined range.

A peak area display method including:

• acquiring measurement data measured by a chromatograph;
• fitting a model function to a chromatogram to obtain a maximum value or a minimum value of a peak area by performing optimization calculation to maximize or minimize the peak area while keeping a value to be taken by a loss function representing a residual between the chromatogram obtained from the measurement data and the model function in a predetermined range;
• and
• displaying a maximum value or a minimum value of the peak area, or information obtained by a process of the maximum value or the minimum value of the peak area.

A peak area calculation method including:

• acquiring measurement data measured by a chromatograph;
• and
• fitting a model function to a chromatogram to obtain a maximum value or a minimum value of a peak area by performing optimization calculation to maximize or minimize the peak area calculated based on the model function while keeping a value to be taken by a loss function representing a residual between the chromatogram obtained from the measurement data and the model function in a predetermined range,
• wherein the performing of the optimization calculation comprises:
• calculating a minimum loss value representing the residual between the chromatogram and the model function,
• setting a predetermined range between the minimum loss value and a value obtained by adding a predetermined value to the minimum loss value, and
• calculating the maximum value or the minimum value of the peak area by varying a parameter of the model function under a constraint condition that the residual between the chromatogram and the model function is within the predetermined range.