Back to results
US 12,612,646 B2Granted
DNA vectors and elements for sustained gene expression in eukaryotic cells
AssigneeDna Twopointo Inc.
InventorsJeremy Minshull, Maggie Lee
Life of this patent
Estimating the term…
Abstract
The present invention provides polynucleotide vectors for high expression of heterologous genes. Some vectors further comprise novel elements that further improve expression. The gene transfer systems can be used in methods, for example, gene expression, bioprocessing, gene therapy, insertional mutagenesis, or gene discovery.
Claims8
A polynucleotide comprising a posttranscriptional regulatory element (PRE) comprising the sequence of SEQ ID NO:313 in operable linkage to an open reading frame or an RNA-encoding sequence, said PRE is positioned 3′ to the open reading frame or RNA-encoding sequence.
Dependencies are inferred from the claim text.