US 12,612,431 B2Granted

Cyclic compounds for treating cancer

AssigneeUniversity of South Florida

InventorsJianfeng Cai, Mengmeng Zheng

Life of this patent

Estimating the term…

Provided are cyclic peptidomimetics that can, e.g., antagonize the extracellular domain of EGFR, and methods of use thereof.

Dependent claims

A compound M-2-5 having the structure:

Dependencies are inferred from the claim text.

C07K 7/56
With at least one abnormal peptide link in the ring: the cyclisation not occurring through 2,4-diamino-butanoic acid
A61P 35/00
Antineoplastic agents
C07K 7/02
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof: linear peptides containing at least one abnormal peptide link
A61K 38/00
Medicinal preparations containing peptides

From the US filing history. Foreign family members aren’t listed.

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