Aryl glucoside derivative

A compound of formula (I-1), or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof,

• wherein, R1a, R1b and R1c are each independently F, —OR1A, or —NHR1A, wherein R1A is independently hydrogen, C1-C6 alkyl, or acyl;
• R2 is S(O)m—R1A, and m=0, 1, or 2;
• R3, R4, R5, R6, R7, R8 and R9 are each independently hydrogen, deuterium, halogen, C1-C6 alkyl, cycloalkyl, cycloalkylalkyl, acyl, or alkynylalkyl;
• m2=1, 2, or 3;
• n2=1;
• X is hydrogen, deuterium, halogen, C1-C6 alkyl, C3-C6 cycloalkyl, C2-C6 alkenyl, or C2-C6 alkynyl;
• and
• Y1 is a linking group represented by any one of the following structures:
• wherein, RE, RF, RG and RH are each independently hydrogen, deuterium, halogen, C1-C6 alkyl, or acyl;
• E and J are each independently a single bond, —CH2—, oxygen, and or —NH—;
• s1=0, 1, 2, 3, 4, or 5;
• s2=0, 1, 2, 3, 4, or 5;
• and
• s3=0, 1, 2, 3, 4, or 5.