Salts and solid forms of 4-hydroxy-N,N-diisopropyltryptamine hemi-glutarate and hemi-succinate
AssigneeTerran Biosciences Inc.
InventorSamuel Clark
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Abstract
Disclosed herein are salts and solid forms of 4-hydroxy-N,N-diisopropyltryptamine hemi-glutarate (4-OH-DIPT), e.g., 4-OH-DIPT hemi-glutarate, 4-OH-DIPT hemi-succinate, 4-OH-DIPT hemi-succinate hydrochloride, and 4-OH-DIPT hemi-glutarate hydrochloride. The solid form may be a salt and/or a crystalline form of the 4-OH-DIPT, such as a polymorph of 4-OH-DIPT or a salt thereof. Also disclosed are methods for making the solid forms and methods for administering the solid forms. The disclosed solid forms of 4-OH-DIPT are useful for treating neurological disease and/or a psychiatric disorder in a subject.
Claims6
A crystalline solid form of 4-OH-DIPT hemi-glutarate hydrochloride characterized by having two or more X-ray powder diffraction peaks at diffraction angles 2θ (°) selected from the group consisting of 18.4±0.2, 23.3±0.2, and 24.9±0.2, as measured by X-ray diffractometry by irradiation with Cu-Kα X-rays.
Dependencies are inferred from the claim text.