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US 12,612,358 B2Granted
Resorcinol-based compounds and uses thereof
AssigneesSutter Bay Hospitals, Organix, Inc.
InventorsSean D. McAllister, Pierre-Yves Desprez, Anuradha Mahadevan, Ravi K. Ujjinamatada
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Abstract
The disclosure provides for resorcinol-based compounds, pharmaceutical compositions made therefrom, and methods of treatment thereof for various disorders, including neoplastic disorders.
Claims19
A resorcinol-based compound having the structure of:
- or a pharmaceutically acceptable salt, or prodrug thereof, wherein:
- L1 is
- R1 is selected from
- R2, R4, R6, and R7 are each independently selected from H or a (C1-C3) alkyl;
- R3 and R5 are each independently selected from H, hydroxyl, a (C1-C3) alkyl, and a halo;
- R8 is selected from an optionally substituted (C1-C12) alkyl, an optionally substituted (C1-C11) hetero-alkyl, an optionally substituted (C1-C12) alkenyl, an optionally substituted (C1-C11) hetero-alkenyl, an optionally substituted (C1-C12) alkynyl, an optionally substituted (C1-C11) hetero-alkynyl, an optionally substituted aryl, an optionally substituted (C3-C12) cycloalkyl, an optionally substituted (C3-C12) cycloalkenyl, and an optionally substituted heterocycle;
- and
- R9 is selected from H, and a (C1-C3) alkyl.
5 more elements
Dependencies are inferred from the claim text.