Sample holder, loading device, and method for inserting a sample into a sample holder

A sample holder comprising:

• a main component comprising a first surface area for receiving a sample thereon;
• and
• a retaining mechanism comprising a clamp and a spring, wherein the clamp comprises a bottom component and a holding component, the sample being disposed between the holding component and the first surface area, the spring being disposed between the main component and the bottom component,
• wherein the retaining mechanism is configured to retain the sample in the sample holder in a closed state of the retaining mechanism such that the sample is clamped by the holding component against the first surface area via the spring,
• wherein the retaining mechanism is configured to enter an opened state upon mechanical actuation of the retaining mechanism, the opened state allowing insertion and removal of the sample, and wherein the retaining mechanism is configured to revert to the closed state once the mechanical actuation is removed.