Systems and methods for simultaneously measuring diffusion weighted spin-echo and stimulated echo signals
AssigneeUniversity of Utah Research Foundation
InventorsEun-Kee Jeong, Kyle Jeong, John W. Rose
Life of this patent
Estimating the term…
Abstract
A method for applying a diffusion-weighting gradient during acquisition of diffusion-weighted imaging signals from a selected portion of a nervous system of a subject. Planar diffusion-weighted spin-echo (DWSE) imaging signals and planar diffusion-weighted stimulated-echo (DWSTE) imaging signals can be obtained to provide a plurality of sets of imaging signals. At least one set of imaging signals includes DWSTE signals that are associated with a high-b-value. A signal difference between DWSE imaging signals and DWSTE imaging signals can be corrected based on respective sets of DWSE imaging signals and DWSTE imaging signals having b-values at or near zero.
Claims20
A method comprising:
- (a) applying, using at least one processing unit of an MRI system, a diffusion-weighting gradient during acquisition of diffusion-weighted imaging signals from a selected portion of a nervous system of a subject;
- (b) obtaining, simultaneously from the MRI system, planar diffusion-weighted spin-echo (DWSE) imaging signals and planar diffusion-weighted stimulated-echo (DWSTE) imaging signals to provide a plurality of sets of imaging signals, wherein the plurality of sets of imaging signals comprise a first set of DWSE imaging signals associated with a first low-b-value that is at or near zero, a first set of DWSTE imaging signals associated with a second low-b-value that is at or near zero, and a second set of DWSTE signals that are associated with a high-b-value, wherein the high-b-value is at or above 3,000 s/mm2;
- and
- (c) correcting, based on the first set of DWSE imaging signals and the first set of DWSTE imaging signals, a signal difference between the DWSE imaging signals and the DWSTE imaging signals.
A system comprising:
- a magnetic resonance imaging system that is configured to:
- apply a diffusion-weighting gradient during acquisition of diffusion-weighted imaging signals from a selected portion of a nervous system of a subject,
- obtain, simultaneously from the MRI system, planar diffusion-weighted spin-echo (DWSE) imaging signals and planar diffusion-weighted stimulated-echo (DWSTE) imaging signals to provide a plurality of sets of imaging signals, wherein the plurality of sets of imaging signals comprise a first set of DWSE imaging signals associated with a first low-b-value that is at or near zero, a first set of DWSTE imaging signals associated with a second low-b-value that is at or near zero, and a second set of DWSTE signals that are associated with a high-b-value, wherein the high-b-value is at or above 3,000 s/mm2;
- and
- a memory;
- and
- at least one processor in communication with the memory,
- wherein the memory comprises instructions that, when executed by the at least one processor, cause the processor to correct, based on the first set of DWSE imaging signals and the first set of DWSTE imaging signals, a signal difference between the DWSE imaging signals and the DWSTE imaging signals.
A computing device comprising:
- a memory;
- and
- at least one processor in communication with the memory,
- wherein the memory comprises instructions that, when executed by the at least one processor, cause the processor to:
- receive simultaneously obtained planar diffusion-weighted spin-echo (DWSE) imaging signals and planar diffusion-weighted stimulated-echo (DWSTE) imaging signals that are provided as a plurality of sets of imaging signals, wherein the plurality of sets of imaging signals comprise a first set of DWSE imaging signals associated with a first low-b-value that is at or near zero, a first set of DWSTE imaging signals associated with a second low-b-value that is at or near zero, and a second set of DWSTE signals that are associated with a high-b-value, wherein the high-b-value is at or above 3,000 s/mm2;
- and
- correct, based on the first set of DWSE imaging signals and the first set of DWSTE imaging signals, a signal difference between the DWSE imaging signals and the DWSTE imaging signals.
Dependencies are inferred from the claim text.