Electrolytic device noise reduction and lifetime improvement using modulated driver
AssigneeDionex Corporation
InventorsMrinal K. Sengupta, George Tang, Husam Al-Esawi
Life of this patent
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Abstract
Systems and methods are described for ion chromatography systems and electrolytic suppressors. By varying the operating frequency of an electrolytic suppressor, the generation of bubbles and noise can be minimized. This leads to more accurate results in e.g., a conductivity detector downstream of an electrolytic suppressor within an ion chromatography system. In certain embodiments, it has been found that frequencies of around 700-750 Hz, 100-150 Hz and 925-975 Hz have achieved the best results.
Claims32
An electrolytic suppressor system for an ion chromatography system, comprising:
- a signal generator electrically coupled to a power supply and configured to modulate a current from the power supply;
- and
- an electrolytic suppressor configured to suppress eluent conductivity in an ion chromatography system, the electrolytic suppressor electrically coupled to the signal generator and configured to use the modulated current for power,
- wherein the modulated current has a frequency of 700-750 Hz, a frequency of 100-150 Hz, or a frequency of 925-975 Hz.
An electrolytic suppressor system for an ion chromatography system, comprising:
- a signal generator electrically coupled to a power supply and configured to modulate a current from the power supply;
- and
- an electrolytic suppressor configured to suppress eluent conductivity in an ion chromatography system, the electrolytic suppressor electrically coupled to the signal generator and configured to use the modulated current for power,
- wherein the signal generator modulates the current at a frequency based at least in part on a measured noise and measured background stability.
An ion chromatography system comprising:
- a pump configured to receive a liquid under process from a source and to provide force to push the liquid under process through the ion chromatography system;
- an eluent generator downstream of the pump and configured to add an eluent to the liquid under process;
- a continuously regenerated trap column downstream of the eluent generator and configured to remove contaminants from the liquid under process;
- a sample inject downstream of the continuously regenerated trap column and configured receive a test sample and mix the test sample into the liquid under process;
- a separation column downstream of the sample inject and configured to separate one or more components from one or more test analytes of the liquid under process;
- an electrolytic suppressor system comprising;
- a signal generator electrically coupled to a power supply and configured to modulate a current from the power supply, wherein the signal generator modulates the current at a frequency based at least in part on a measured noise and measured background stability;
- and
- an electrolytic suppressor configured to receive the liquid under process from the separation column and to suppress eluent conductivity in the one or more test analytes of the liquid under process, the electrolytic suppressor electrically coupled to the signal generator and configured to use the modulated current for power;
- and
- a detector configured to receive the liquid under process from the electrolytic suppressor and to detect one or more characteristics of the liquid under process.
A method of operating an electrolytic suppressor in an ion chromatography system, the method comprising:
- modulating a current at a predetermined frequency, the current configured to power the electrolytic suppressor;
- and
- powering the electrolytic suppressor with the modulated current, the electrolytic suppressor configured to suppress eluent conductivity in one or more test analytes of a liquid under process.
A method of operating an ion chromatography system, the method comprising:
- receiving a liquid under process at a pump;
- pumping the liquid under process through the system;
- adding, by an eluent generator, an eluent to the liquid under process;
- removing, by a continuously regenerated trap column, contaminants from the liquid under process;
- receiving, at a sample inject, a test sample into the liquid under process;
- separating, by a separation column, one or more components from one or more test analytes in the liquid under process;
- modulating at a predetermined frequency, by a signal generator, a current received from a power supply;
- powering one or more components in the ion chromatography system with the modulated current, wherein the one or more components comprises at least one of an electrolytic suppressor;
- the eluent generator;
- or the continuously regenerated trap column;
- suppressing, by the electrolytic suppressor, eluent conductivity of the one or more test analytes in the liquid under process;
- and
- detecting, by a conductivity detector, one or more characteristics in the liquid under process.
Dependencies are inferred from the claim text.