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US 12,607,594 B2Granted
ISFET biosensor
AssigneeTexas Instruments Incorporated
InventorSebastian Meier
Life of this patent
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Abstract
In described examples, a biosensor device has a porous membrane with a test region that contains a test analyte. A sensor die has an ion sensing field effect transistor (ISFET) with an ion sensitive gate element located in an active sensor surface of the sensor die. The active sensor surface is in contact with the porous membrane test region. A controller is coupled to the ISFET and an interface module is coupled to the controller to provide a human readable test result.
Claims14
An apparatus comprising:
- a substrate having opposite first and second surfaces, and a first opening and a second opening through the substrate;
- a porous membrane on the first surface, the porous membrane having a first membrane region that contains a test analyte and a second membrane region that contains a reference analyte, at least a part of the first membrane region being over the first opening, and at least a part of the second membrane region being over the second opening;
- a first seal structure in the first opening;
- a second seal structure in the second opening;
- a first sensor mounted on the second surface and on the first seal structure, the first sensor having a first ion sensing field effect transistor (ISFET) having a first ion sensitive gate element located in a first active sensor surface of the first sensor, wherein the first active sensor surface is exposed in the first opening and is surrounded by the first seal structure;
- a second sensor mounted on the second surface and on the second seal structure, the second sensor having a second ISFET having a second ion sensitive gate element located in a second active sensor surface of the second sensor, wherein the second active sensor surface is exposed in the second opening and is surrounded by the second seal structure;
- a controller mounted on the substrate and coupled to the first ISFET and to the second ISFET;
- and
- an interface module mounted on the substrate and coupled to the controller.
6 more elements
An apparatus comprising:
- a substrate having opposite first and second surfaces and an opening through the substrate;
- a seal structure in the opening;
- a sensor die mounted on the first surface and on the seal structure, the sensor die having at least one ion sensing field effect transistor (ISFET) having an ion sensitive gate element located in an active sensor surface of the sensor die, wherein the active sensor surface is exposed in the opening and is surrounded by the seal structure;
- a porous membrane having a membrane region that contains an analyte, in which the membrane region extends through the opening and contacts the active sensor surface;
- a controller mounted on the substrate and coupled to the ISFET;
- and
- an interface module mounted on the substrate and coupled to the controller.
4 more elements
Dependencies are inferred from the claim text.