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US 12,606,875 B2Granted
Fish Totivirus
AssigneePharmaq AS
InventorsStian Nylund, Liv Sandlund, Arnfinn L. Okland
Life of this patent
Estimating the term…
Abstract
The invention relates to a novel fish virus, indicated to be a Totivirus, which causes mortality in fish, and to methods of detecting said virus in fish, and related uses.
Claims22
A nucleic acid, wherein the sequence of said nucleic acid comprises at least one open reading frame (ORF) sequence selected from the group consisting of ORF-1, ORF-2, ORF-X,
- ORF-Y and ORF-Z;
- wherein
- ORF-1 is at least 80% identical to the nucleic acid sequence of SEQ ID NO:1,
- ORF-2 is at least 80% identical to the nucleic acid sequence of SEQ ID NO:2,
- ORF-X is at least 80% identical to the nucleic acid sequence of SEQ ID NO:3,
- ORF-Y is at least 80% identical to the nucleic acid sequence of SEQ ID NO:4, and
- ORF-Z is at least 80% identical to the nucleic acid sequence of SEQ ID NO:5.
4 more elements
A nucleic acid, wherein
- (a) the sequence of said nucleic acid is complementary to SEQ ID NO:
- 1 and/or to SEQ ID NO:
- 2;
- and/or
- (b) the sequence of said nucleic acid is complementary to SEQ ID NO:
- 6.
3 more elements
A method for detecting a virus that infects and is capable of killing fish, comprising the steps of:
- (a) sequencing a nucleic acid extracted from a biological sample of a fish, and
- (b) comparing the resulting nucleic acid sequence with a nucleic acid sequence which is, or which is complementary to, a reference sequence selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6, wherein an at least 80% sequence identity between the two sequences indicates the presence of the virus in the biological sample.
A viral polypeptide comprising an amino acid sequence that is at least 80% identical to any one of SEQ ID NOS 7-11.
Dependencies are inferred from the claim text.