Biocatalysts for organic synthesis

A biocatalyst for organic synthesis, comprising:

• (a) a controlled porosity silica (CPS) as support material;
• wherein the support material comprises an amino-functionalized surface comprising the following structure
• and
• (b) a Thermomyces lanuginosus lipase immobilized to the surface via non-covalent interactions;
• wherein the support material has a pore diameter from about 20 nm to about 60 nm, a surface area from about 50 m2/g to about 200 m2/g, and a pore volume from about 0.5 mL/g to about 2.0 mL/g.