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US 12,606,627 B2Granted
α4β7 integrin binding proteins and methods of use
AssigneeParagon Therapeutics, Inc.
InventorsEric Franklin Zhu, Hussam Hisham Shaheen, Jacob Cole Milligan
Life of this patent
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Abstract
Provided herein are α4β7 binding proteins (e.g., antibodies that bind α4β7) and methods of use.
Claims15
An α4β7 binding antibody
- comprising a heavy chain variable domain (VH) comprising the amino acid sequence of SEQ ID NO:
- 1909, and comprising a light chain variable region (VL) comprising the amino acid sequence of SEQ ID NO:
- 2015, or
- comprising a heavy chain variable domain (VH) comprising the amino acid sequence of SEQ ID NO:
- 1910, and comprising a light chain variable region (VL) comprising the amino acid sequence of SEQ ID NO:
- 2016.
3 more elements
An α4β7 binding antibody protein comprising:
- a) a heavy chain variable region (VH) comprising the amino acid sequence according to SEQ ID NO:
- 1909;
- and
- b) a light chain variable region (VL) comprising the amino acid sequence according to SEQ ID NO:
- 2015.
2 more elements
An α4β7 binding antibody comprising:
- a) a heavy chain variable region (VH) comprising the amino acid sequence according to SEQ ID NO:
- 1910;
- and
- b) a light chain variable region (VL) comprising the amino acid sequence according to SEQ ID NO:
- 2016.
2 more elements
Dependencies are inferred from the claim text.