Anti-FGF23 antibody or antibody fragment thereof
AssigneeKyowa Kirin Co., Ltd.
InventorsHikaru Miyagi, Taiji Oashi, Kenta Nakajima, Sari Ogasawara
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Abstract
The present invention relates to an antibody or an antibody fragment thereof which binds to FGF23. The antibody comprises a heavy chain variable region (hereinafter, described as VH) comprising the amino acid sequence represented by SEQ ID NO: 1 and a light chain variable region (hereinafter, described as VL) comprising the amino acid sequence represented by SEQ ID NO: 2. At least the amino acid residue at position 100 or the amino acid residue at position 105 of the amino acid sequence represented by SEQ ID NO: 1 in the VH is substituted with another amino acid residue.
Claims6
An antibody or an antibody fragment thereof which binds to FGF23, wherein the antibody comprises a heavy chain variable region (VH) comprising the amino acid sequence represented by SEQ ID NO:
- 39 and a light chain variable region (VL) comprising the amino acid sequence represented by SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.