Back to results
US 12,606,592 B2Granted
Triple G-C-T base coded nucleobase amino acid, its synthesis and peptide formation
AssigneeCouncil of Scientific and Industrial Research
InventorsMahendra Ashok Wagh, Gangadhar Jessy Sanjayan
Life of this patent
Estimating the term…
Abstract
Triple G-C-T base coded nucleobase amino acids according to Formula (I): wherein R is —H or -Boc, are provided as building blocks for peptide sequences. The compound of formula (I) includes three recognition sites, DDA (G mimic), DAA (C mimic) and ADA (T mimic) that can simultaneously interact with two sets of nucleobases (C-A or G-A), at any given time. A one-step synthetic process for the triple G-C-T base coded nucleobase amino acids is provided.
Claims10
A triple G-C-T base coded nucleobase amino acid, comprising a compound according to formula (I):
- where R is —H or -Boc,
- wherein:
- the triple G-C-T base coded nucleobase amino acid comprises three recognition sites that can simultaneously interact with two sets of nucleobases at any given time;
- the three recognition sites comprise DDA as a G mimic, DAA as a C mimic, and ADA as a T mimic;
- and
- the two sets of nucleobases comprise C-A and G-A.
3 more elements
Dependencies are inferred from the claim text.