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US 12,606,578 B2Granted
Crystal form of spirocyclic amine aryl phosphorus oxide compound and preparation method therefor
AssigneeQilu Pharmaceutical Co., Ltd.
InventorsZhaofeng Ding, Qiang Fu
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Abstract
The present invention relates to a crystal form of a compound of Formula (I), i.e. (2-((5-chloro-2-((2-methoxy-4-(9-methyl-3,9-diaza-spiro[5.5]undecan-3-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide. The present invention further relates to a pharmaceutical composition of the crystal form, and the pharmaceutical use thereof and a preparation method therefor.
Claims10
A crystal form Q4 of a compound of Formula (I),
- wherein an X-ray powder diffraction spectrum of the crystal form Q4 has a characteristic peak at 2θ values of 10.19, 14.27, 14.79, 16.14, 19.45 and 27.32, using Cu-Kα radiation, and the 2θ error range is ±0.2°.
Dependencies are inferred from the claim text.