Alkaloid-containing compositions and uses thereof

A composition comprising at least about 10 g/L of one or more loline alkaloids having the structure of Formula [I]:

• wherein R═H or CH3 and R′═H, CH3, CHO or COCH3, the one or more loline alkaloids comprising N-formylloline having the structure of Formula [II]:
• and one or more solvents;
• wherein
• a) the molar ratio of total hydroxyl groups and nitrogen-containing groups to N-formylloline of the composition is less than about 20, or
• b) the molar ratio of total hydroxyl groups and nitrogen-containing groups to N-formylloline of the composition is greater than about 20, and wherein the nucleophilicity coefficients of the hydroxyl groups or nitrogen-containing groups of the composition are less than about 0.6 eV;
• wherein the nitrogen-containing groups are selected from ammonia, a primary amine group, a secondary amine group, or mixtures thereof;
• wherein the one or more solvents are selected from the group consisting of:
• 1) polyalkylene glycols, or ethers or esters thereof;
• 2) propylene glycol;
• 3) dimethyllactamide;
• 4) cyclohexanol;
• 5) benzyl alcohol;
• 6) glycerine carbonate;
• 7) butyl benzoate and/or ethyl lactate;
• and
• 8) triethylcitrate,
• wherein at least about 50% w/w of the total solvents of the composition consists of the one or more solvents.