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US 12,606,523 B2Granted
Deuterated organic compounds and uses thereof
AssigneeEngrail Therapeutics, Inc.
InventorsKrishna Vadodaria, Kimberly Vanover, Jordi Serrats, Vikram Sudarsan, David Garvey
Life of this patent
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Abstract
Provided are compounds of Formula I, described herein, processes for their preparation, their use as pharmaceuticals, and pharmaceutical compositions comprising them and intermediates used in their preparation. Compounds of Formula I are useful, for instance, in modulating dopamine neurotransmission and treating disorders that may benefit from the same, such as schizophrenia and depression.
Claims17
A compound of Formula I:
- wherein:
- R1, R2, R3, R4, and R5 are independently selected from H and D;
- and
- at least one of R1, R2, and R3 is D;
- in free or salt form.
2 more elements
A compound, wherein the compound is:
- in free or pharmaceutically acceptable salt form.
Dependencies are inferred from the claim text.