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AssigneeNanjing Heron Pharmaceutical Science and Technology Co., Ltd.
InventorsHai Ye, Wenliang Zhou, Jialin Wang, Ying Xu, Tao Min, Tian Lv, Xingran Chen
Estimating the term…
The application related to an ibuprofen ester derivative and an emulsion preparation thereof. A carboxyl group of racemic ibuprofen or S-ibuprofen is derivatized so that Compound N9 and a dextrorotatory enantiomer N9(S) thereof are obtained and further prepared into an emulsion preparation, which overcomes the problems of safety and compliance of patients existing in clinical application of existing ibuprofen/dexibuprofen injections and achieves the purposes of reducing vascular irritation, increasing clinical use approaches, and improving the stability of preparations in clinical applications.
An ibuprofen ester derivative, a racemate, stereoisomer, or pharmaceutically acceptable salt thereof, wherein the ibuprofen ester derivative is a compound represented by Structural Formula (1):
An emulsion preparation containing an ibuprofen ester derivative, comprising:
Dependencies are inferred from the claim text.