Delivery machine limitation guided radiation therapy treatment planning

A system for planning a radiation therapy treatment to be performed by a radiation therapy machine, the system comprising:

• a memory storing computer executable instructions;
• and
• at least one processor configured to execute the computer executable instructions to cause the system to
• determine a plurality of minimum monitor unit values based on a minimum monitor unit saturation curve for the radiation therapy machine, the minimum monitor unit saturation curve derived based on machine parameters for the radiation therapy machine, and
• generate a radiation therapy treatment plan prescribing a plurality of energy layers associated with a plurality of spots in a treatment target, the radiation therapy treatment plan being based on the plurality of minimum monitor unit values, each of the plurality of minimum monitor unit values being for a respective energy layer among the plurality of energy layers, and each of the plurality of minimum monitor unit values being based on the machine parameters for the radiation therapy machine.