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US 12,605,520 B2Granted
Delivery of ultra pure nitric oxide (NO)
AssigneeVERO Biotech Inc.
InventorsDavid H. Fine, Gregory Vasquez, Bryan Johnson, Ryan Denton, Lucas G. Gamero
Life of this patent
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Abstract
A system for delivering a therapeutic amount of nitric oxide can include a reservoir including a restrictor with a length of at least 0.5 inches and at most 2 inches covered by a metal sheath, a gas supply, and a delivery conduit. A delivery conduit can include at least one cartridge and a patient interface. The at least one cartridge can include a surface-active material and a reducing agent.
Claims15
A disposable module comprising:
- a restrictor connected to a reservoir comprising a source of nitrogen dioxide gas, wherein the restrictor has a dimension defined by a total pressure drop effective to provide a predetermined amount of nitrogen dioxide gas;
- and wherein the restrictor and the reservoir are configured to be heated to a temperature of at most 200° C., and
- at least one cartridge configured to receive the predetermined amount of nitrogen dioxide gas through the restrictor and to form a therapeutic amount of nitric oxide.
A method, comprising:
- heating to a temperature of at most 200° C. a reservoir comprising a source of nitrogen dioxide to form the nitrogen dioxide;
- passing a predetermined amount of nitrogen dioxide through a restrictor to at least one cartridge, wherein the predetermined amount of nitrogen dioxide is defined by the restrictor's dimension;
- and
- forming a therapeutic amount of nitrogen oxide in the at least one cartridge.
1 more element
Dependencies are inferred from the claim text.