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US 12,605,519 B2Granted
Process and signal processing unit for determining the breathing activity of a patient
AssigneeDrägerwerk AG & Co. KGaA
InventorsMarcus Eger, Thomas Handzsuj, Philipp Rostalski, Eike Petersen
Life of this patent
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Abstract
A process and a signal processing unit for determining a first pneumatic indicator (Pmus,1) and a second pneumatic indicator (Pmus,2) for the breathing activity of a patient, wherein the two values describe the activity of two different regions of the respiratory system. In one alternative of the present invention, two respiratory signals (Sig1, Sig2) are generated from measured values. The two values (Pmus,1, Pmus,2) are determined with the use of these respiratory signals (Sig1, Sig2) and of a predefined function (Fkt) and of predefined relationships (Zus1, Zus2).
Claims19
A process for determining a first pneumatic indicator and a second pneumatic indicator for the breathing activity of a patient,
- wherein
- the first pneumatic indicator describes activity of a first region of a respiratory system of the patient and/or of a first process during breathing by the patient and
- the second pneumatic indicator describes activity of a second region of the respiratory system of the patient and/or of a second process during the breathing by the patient, the second region being different from the first region and/or the second process being different from the first process,
- wherein a predefined airway pressure function, which describes a measurable indicator for an airway pressure, wherein the airway pressure is achieved by an overall intrinsic breathing activity of the patient and/or by mechanical ventilation of the patient, is predefined in a computer-accessible form as a function of at least:
- a volume flow indicator for a volume flow of breathing air relative to the patient and/or
- a filling level indicator for a filling level of the lungs of the patient as well as
- a function of the first pneumatic indicator and the second pneumatic indicator to be determined and/or of an overall pneumatic indicator for the overall breathing activity of the patient,
- wherein
- a first relationship between the first pneumatic indicator and a first measurable respiratory signal and/or
- a second relationship between the second pneumatic indicator and a second measurable respiratory signal and/or
- an overall relationship between the overall pneumatic indicator for the overall breathing activity of the patient and an overall measurable respiratory signal are predefined in a computer-accessible form,
- wherein at least one of the first and second relationships and/or the overall relationship has a model parameter and
- wherein the process comprises steps that
- the patient is at least temporarily connected to an airway pressure sensor, which measures the measurable indicator for the airway pressure,
- a signal processing unit
- receives measured values of the airway pressure sensor while the patient is connected to the airway pressure sensor and generates an airway pressure signal with the use of at least some of the values measured by the airway pressure sensor and
- uses a predefined value for the airway pressure as an airway pressure signal while the patient is not connected to the airway pressure sensor, the signal processing unit
- receives values measured by a volume flow sensor during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient, the volume flow sensor measures the volume flow indicator for the volume flow of breathing air and generates a volume flow signal from at least some of the values measured by the volume flow sensor, and/or
- receives values measured by a filling level sensor during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient, the filling level sensor measures the filling level indicator for the filling level of the lungs of the patient, and generates a volume signal from at least some of the values measured by the filling level sensor,
- a first and/or a second and/or a third sequence are carried out during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient:
- in the first sequence, the signal processing unit
- receives values measured by a first breathing sensor, wherein the measured values pertain to an indicator that is correlated with the first pneumatic indicator,
- generates the first measurable respiratory signal from at least some of the values measured by the first breathing sensor,
- derives a value for the model parameter, which occurs in the first relationship, with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function, and
- determines the first pneumatic indicator with the use of the first relationship and of the value of the model parameter occurring in the first relationship,
- in the second sequence the signal processing unit
- receives values measured by a second breathing sensor, wherein the measured values pertain to an indicator that is correlated with the second pneumatic indicator,
- generates the second measurable respiratory signal from at least some of the values measured by the second breathing sensor,
- derives a value for the model parameter that occurs in the second relationship with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function, and
- determines the second pneumatic indicator with the use of the second relationship and of the respective value of the model parameter occurring in the second relationship, in the third sequence the signal processing unit
- receives measured values from an overall breathing sensor, wherein the measured values pertain to an indicator that is correlated with the overall pneumatic indicator,
- generates the overall measurable respiratory signal from values measured by the overall breathing sensor,
- derives a value for the model parameter that occurs in the overall relationship with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function, and
- determines the overall pneumatic indicator with the use of the overall relationship and of the derived value of the model parameter occurring in the overall relationship,
- wherein the signal processing unit is configured such that in the case that one of the first pneumatic indicator or the second pneumatic indicator as well as the overall pneumatic indicator have been determined, but the other one of the first pneumatic indicator or the second pneumatic indicator has not been determined,
- the signal processing unit determines the other one of the first pneumatic indicator or the second pneumatic indicator with the use of the one of the first pneumatic indicator or the second pneumatic indicator already determined and of the overall pneumatic indicator already determined,
- wherein the signal processing unit is configured such that in the case that the one of the first pneumatic indicator or the second pneumatic indicator has been determined but neither the overall pneumatic indicator nor the other one of the first pneumatic indicator or the second pneumatic indicator have been determined,
- the signal processing unit
- determines the overall pneumatic indicator with the use of the one of the first pneumatic indicator or the second pneumatic indicator that has been determined as well as the volume flow signal;
- and/or the volume signal and/or a predefined percentage function, and
- determines the other one of the first pneumatic indicator or the second pneumatic indicator with the use of the one of the first pneumatic indicator or the second pneumatic indicator that has been determined and the overall pneumatic indicator, and
- wherein the signal processing unit is configured such that in the case that the overall pneumatic indicator has been determined, but neither the first pneumatic indicator nor the second pneumatic indicator has been determined, the signal processing unit determines the first pneumatic indicator and the second pneumatic indicator with the use of the overall pneumatic indicator as well as of the volume flow signal and/or of the volume signal and/or of the predefined percentage function.
39 more elements
A signal processing unit for determining by calculation a first pneumatic indicator and a second pneumatic indicator for the breathing activity of a patient,
- wherein
- the first pneumatic indicator describes activity of a first region of the respiratory system of the patient and/or of a first process during breathing by the patient and
- the second pneumatic indicator describes activity of a second region of the respiratory system of the patient and/or of a second process during breathing by the patient, the second region being different from the first region and/or the second process being different from the first process,
- wherein the signal processing unit has at least temporarily reading access to a memory, in which memory, a predefined airway pressure function is stored in a computer-accessible form,
- wherein the airway pressure function describes a measurable indicator for an airway pressure, wherein the airway pressure is achieved by an overall intrinsic breathing activity of the patient and/or by mechanical ventilation of the patient, as a function of at least
- a volume flow indicator for a volume flow of breathing air relative to the patient and
- a filling level indicator for a filling level of the lungs of the patient as well as
- a function of the first pneumatic indicator and the second pneumatic indicator to be determined and/or of an overall pneumatic indicator for an overall breathing activity of the patient,
- wherein furthermore
- a predefined first relationship between the first pneumatic indicator and a first measurable respiratory signal and/or
- a predefined second relationship between the second pneumatic indicator and a second measurable respiratory signal and/or
- an overall relationship between the overall pneumatic indicator for the overall breathing activity of the patient and a measurable overall respiratory signal are stored in the memory in a computer-accessible form,
- wherein at least one of the predefined first and second relationships and/or the overall relationship has a model parameter and
- wherein the patient can be connected or is at least temporarily connected to an airway pressure sensor, which sensor is configured to measure the measurable indicator for the airway pressure, wherein the signal processing unit is configured
- to receive measured values from the airway pressure sensor while the patient is connected to the airway pressure sensor and to generate the airway pressure signal with the use of at least some of the values measured by the airway pressure sensor and
- to use a predefined value for the airway pressure as an airway pressure signal while the patient is not connected to the airway pressure sensor,
- wherein the signal processing unit is configured
- to receive values measured by a volume flow sensor during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient, the volume flow sensor being configured to measure a volume flow indicator for a volume flow of breathing air, and to generate a volume flow signal from at least some of the values measured by the volume flow sensor and/or
- to receive values measured by a filling level sensor during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient, the filling level sensor being configured to measure the filling level indicator for a filling level of the lungs, and to generate a volume signal from the at least some of the values measured by the filling level sensor,
- wherein the signal processing unit is configured to carry out a first and/or a second and/or a third sequence during the overall intrinsic breathing activity of the patient and/or the mechanical ventilation of the patient,
- wherein the first sequence comprises steps that the signal processing unit
- receives values measured by a first breathing sensor, wherein these measured values pertain to an indicator that is correlated with the first pneumatic indicator,
- generates the first measurable respiratory signal from these measured values,
- derives a respective value for the model parameter, which occurs in the first relationship, with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function,
- determines the first pneumatic indicator with the use of the first relationship and of the derived value for the model parameter occurring in the first relationship and wherein the second sequence comprises the steps that the signal processing unit
- receives values measured by a second breathing sensor, wherein these measured values pertain to an indicator that is correlated with the second pneumatic indicator,
- generates the second measurable respiratory signal from at least some of the-values by the second breathing sensor,
- derives a respective value for the model parameter, which occurs in the second relationship, with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function, and
- determines the second pneumatic indicator with the use of the second relationship and of the derived value of the model parameter occurring in the second relationship,
- wherein the third sequence comprises the steps that the signal processing unit
- receives measured values from an overall breathing sensor, wherein the measured values pertain to an indicator that is correlated with the overall pneumatic indicator,
- generates the overall measurable respiratory signal from at least some of the values measured by the overall breathing sensor,
- derives a value for the model parameter, which occurs in the overall relationship, with the use of the airway pressure function and of generated signals, which signals occur in the airway pressure function, and
- determines the overall pneumatic indicator with the use of the overall relationship and of the derived value of the model parameter occurring in the overall relationship, wherein in the case that one of the first pneumatic indicator or the second pneumatic indicator, and the overall pneumatic indicator have been determined but the other of the one of the first pneumatic indicator or the second pneumatic indicator has not been determined, the signal processing unit is configured to determine the other of the one of the first pneumatic indicator or the second pneumatic indicator with the use of one of the first pneumatic indicator or the second pneumatic indicator, and the overall pneumatic indicator that has already been determined then, when the one pneumatic value and the overall pneumatic value have been determined but the other pneumatic value has not been determined,
- in the case that the one of the first pneumatic indicator or the second pneumatic indicator has been determined but neither the overall pneumatic indicator nor the other pneumatic indicator has been determined, the signal processing unit is configured
- to determine the overall pneumatic indicator with the use of the already determined pneumatic indicator as well as of the volume flow signal and/or of the volume signal and/or of a predefined percentage function and
- to determine the other pneumatic indicator with the use of the already determined pneumatic indicator and of the overall pneumatic indicator, and
- in the case that the overall pneumatic indicator has been determined but neither the first pneumatic indicator nor the second pneumatic indicator have been determined, the signal processing unit is configured
- to determine the first pneumatic indicator and the second pneumatic indicator with the use of the overall pneumatic indicator as well as of the volume flow signal and/or of the volume signal and/or of a predefined percentage function.
36 more elements
A process for controlling a ventilator, the process comprising:
- determining a first pneumatic indicator and a second pneumatic indicator for breathing activity of a patient, wherein the first pneumatic indicator describes activity of a first region of a respiratory system of the patient and/or of a first process during breathing by the patient, and the second pneumatic indicator describes activity of a second region of the respiratory system of the patient and/or of a second process during the breathing by the patient, the controlling process comprising the steps of:
- providing a predefined airway pressure function which describes a measurable indicator for an airway pressure, where the airway pressure is achieved by overall intrinsic breathing activity and/or mechanical ventilation of the patient, the airway pressure function being predefined as a function of a volume flow indicator for the volume flow of breathing air relative to the patient and/or a filling level indicator for a filling level of lungs of the patient, the airway pressure function further being predefined as a function of the first pneumatic indicator and the second pneumatic indicator to be determined and/or of an overall pneumatic indicator for an overall breathing activity of the patient,
- wherein
- a first relationship is predefined between the first pneumatic indicator and a first measurable respiratory signal, and/or
- a second relationship is predefined between the second pneumatic indicator and a second measurable respiratory signal, and/or
- an overall relationship is predefined between the overall pneumatic indicator for the overall breathing activity of the patient and an overall measurable respiratory signal,
- wherein at least one of the first and second relationships or the overall relationship has a model parameter, and
- connecting the patient to an airway pressure sensor which measures the measurable indicator for the airway pressure;
- receiving measured pressure sensor values from the airway pressure sensor;
- by using measured pressure sensor values, generating an airway pressure signal while the patient is connected to the airway pressure sensor;
- using a predefined value for the airway pressure as the airway pressure signal while the patient is not connected to the airway pressure sensor;
- receiving measured values from a volume flow sensor, which measures the volume flow indicator for a volume flow of breathing air, and generating a volume flow signal from these measured values, and/or receiving measured values from a filling level sensor, which measures the filling level indicator for a filling level of the lungs, and generates a volume signal from these measured values;
- at least one of the following three sequences is carried out,
- in a first sequence receiving measured values from a first breathing sensor, wherein these measured values pertain to an indicator that is correlated with the first pneumatic indicator,
- generating from these measured values the first measurable respiratory signal,
- deriving a value for the model parameter that occurs in the first relationship with the use of the airway pressure function and of generated signals which occur in the airway pressure function, and determining the first pneumatic indicator with the use of the first relationship and of the derived value of the model parameter occurring in the first relationship;
- in a second sequence, receiving measured values from a second breathing sensor, wherein the measured values pertain to an indicator that is correlated with the second pneumatic indicator,
- generating the second measurable respiratory signal from these measured values,
- deriving a value for the model parameter that occurs in the second relationship with the use of the airway pressure function and of generated signals which occur in the airway pressure function, and
- determining the second pneumatic indicator with the use of the second relationship and of the value of the model parameter occurring in the second relationship;
- or
- in a third sequence, receiving measured values from an overall breathing sensor, wherein the measured values pertain to an indicator that is correlated with the overall pneumatic indicator,
- generating the overall measurable respiratory signal from these measured values,
- deriving a value for the model parameter that occurs in the overall relationship with the use of the airway pressure function and of generated signals, which occur in the airway pressure function, and
- determining the overall pneumatic indicator with the use of the overall relationship and of the derived model parameter value;
- wherein a signal processing unit is configured such that in the case that one of the first pneumatic indicator or the second pneumatic indicator and the overall pneumatic indicator have been determined, but the other of the one of the first pneumatic indicator or the second pneumatic indicator has not been determined, the signal processing unit determines the other one of the first pneumatic indicator or the second pneumatic indicator with the use of one of the first pneumatic indicator and the second pneumatic indicator, and the overall pneumatic indicator, that has already been determined, and of the determined overall pneumatic indicator;
- wherein the signal processing unit is configured such that in the case that the one of the first pneumatic indicator or the second pneumatic indicator has been determined but neither the overall pneumatic indicator nor the other of the one of the first pneumatic indicator or the second pneumatic indicator has been determined, the signal processing unit determines the overall pneumatic indicator with the use of the already determined pneumatic indicator as well as of the volume flow signal, and/or of the volume signal and/or of a predefined percentage function, and determines the other of the one of the first pneumatic indicator or the second pneumatic indicator with the use of the already determined pneumatic indicator and of the overall pneumatic indicator;
- and
- wherein the signal processing unit is configured such that in the case that the overall pneumatic indicator has been determined, but neither the first pneumatic indicator nor the second pneumatic indicator has been determined, the signal processing unit determines the first pneumatic indicator and the second pneumatic indicator with the use of the overall pneumatic indicator as well as of the volume flow signal and/or of the volume signal and/or of a predefined percentage function;
- operating the ventilator based on the first pneumatic indicator and/or the second pneumatic indicator.
27 more elements
Dependencies are inferred from the claim text.