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US 12,605,498 B2Granted
Apparatus and methods for extracellular vesicle enrichment
AssigneeHanuman Pelican, Inc.
InventorsRandy Dorian, Michael D. Leach, Richard W. Storrs, Scott R. King
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Abstract
Apparatus and methods for extracellular vesicle enrichment are described in which apparatus may be used to create plasma preparations that are enriched in EV-containing fluid sample. Generally, one variation of a method may generally comprise contacting the fluid sample with a plurality of absorbent chromatographic beads to concentrate EVs from the fluid sample, and separating the beads from the fluid sample.
Claims9
A method of concentrating extracellular vesicles (EV) from an EV-containing fluid sample, comprising:
- contacting the fluid sample with a plurality of absorbent dry-size exclusion chromatographic beads;
- urging the fluid sample with the chromatographic beads in a back-and-forth manner to concentrate EVs from the fluid sample;
- and
- separating the beads from the fluid sample.
1 more element
Dependencies are inferred from the claim text.