Two-component system for the therapeutic treatment of skin lesions and production method thereof

A two-component system for use in the therapeutic treatment of skin lesions, comprising:

• a first component in the form of an aqueous gel and a second component, being a cross-linking agent, in the form of an aqueous solution, wherein
• said first component comprises at least one biocompatible polymer, and at least one polyacid or a salt thereof;
• and
• said second component comprises a saline solution containing a bivalent, trivalent or higher valence cation;
• wherein
• said biocompatible polymer is polyvinyl alcohol with a concentration with respect to said first component between 0.001-30% w/w and with a molecular weight from 10,000 to 1,000,000;
• said polyacid is at least one member selected from the group consisting of polyacrylic acid and sodium alginate;
• said polyacrylic acid having a molecular weight between 400,000 and 5,000,000 and having a concentration with respect to said first component between 0.01-10% w/w;
• said sodium alginate when present having a concentration with respect to said first component of at most 5% w/w, with a viscosity ranging between 50 and 2000 cp at 20° C.;
• and
• wherein application of the first component, in the form of an aqueous gel in a viscous fluid state on the skin of a patient, followed by spraying with the second component in aqueous solution form, induces in situ formation of a film with rubbery consistency and wherein said rubbery film can be removed by washing of the skin with water.