Preparation method for and use method of collagen microfiber hemostatic material

A preparation method of a collagen microfiber hemostatic material, comprising the following steps:

• (1) obtaining a collagen microfiber raw material by performing shearing on a solid collagen material;
• (2) dispersing the collagen microfiber raw material obtained in step (1) in an aqueous phase with a mass ratio of the collagen fiber raw material to water ranging from 1:100 to 1:10,000 to configure a collagen microfiber suspension;
• (3) filtering the collagen microfiber suspension obtained in step (2) through sieves of different meshes to screen and obtain collagen microfibers in a length range of 10-1,000 μm, and dispersing in water to configure the collagen microfiber suspension;
• (4) adding a procoagulant active ingredient to the collagen microfiber suspension obtained in step (3), with a mass ratio of the procoagulant active ingredient to the collagen microfibers ranging from 1:100 to 1:1,000,000;
• (5) adding linking molecules to the collagen microfiber suspension obtained in step (4), wherein the linking molecule is one or a mixture of more than two of sulfonyl chloride, aldehyde, isothiocyanate, carbodiimide, acid anhydride, procyanidin, isocyanate, imide ester, genipin, acyl azide, or epoxide, wherein the final concentration of the linking molecules in the collagen microfiber suspension is greater than or equal to 0.001 wt. % but less than or equal to 1 wt. %, and wherein a time of the linking molecules in the collagen microfiber suspension is 30 min-120 min;
• (6) performing freeze drying on the collagen microfiber suspension obtained in step (5) to obtain a collagen microfiber solid freeze-dried product;
• and
• (7) performing shearing on the collagen microfiber solid freeze-dried product obtained in step (6) through a pulverizer to obtain a dispersible collagen microfiber hemostatic material.