Back to results
US 12,605,448 B2Granted
Porous self-healing polymer matrix for encapsulation of active macromolecules and methods
AssigneeThe Regents of the University of Michigan
InventorsSteven P. Schwendeman, Jason Albert, Rae Sung Chang, George A. Garcia
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a porous self-healing polymer matrix for encapsulation of active macromolecules and a method of manufacturing said porous self-healing polymer matrix for a drug delivery system for a macromolecule.
Claims21
A porous self-healing polymer matrix encapsulating an active macromolecule, comprising:
- a porous self-healing polymer matrix comprising a biodegradable polymer and having pores;
- and,
- an active macromolecule comprising a peptide or a protein;
- and
- an ionic affinity trap disposed within the pores;
- wherein the ionic affinity trap comprises a metal ion, and
- wherein the active macromolecule is covalently bound to a histidine tag.
4 more elements
Dependencies are inferred from the claim text.