Compositions and methods
AssigneeSeres Therapeutics, Inc.
InventorsGregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey Von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
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Abstract
Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Claims20
A therapeutic composition formulated for oral administration comprising a population of bacteria and a capsule, wherein the population of bacteria comprises spore-forming bacteria,
- wherein the population of bacteria comprises a first bacteria and a second bacteria,
- wherein the first bacteria is selected from Clostridium aldenense or a bacterial species having a 16S rDNA sequence with at least 97% identity to SEQ ID NO:
- 547, and
- wherein the second bacteria is selected from Clostridium oroticum or a bacterial species having a 16S rDNA sequence with at least 97% identity to SEQ ID NO:
- 610.
A therapeutic composition formulated for oral administration comprising a population of bacteria and a capsule, wherein the population of bacteria comprises spore-forming bacteria,
- wherein the population of bacteria comprises a first bacteria and a second bacteria,
- wherein the first bacteria is selected from Clostridium aldenense or a bacterial species having a 16S rDNA sequence with at least 97% identity to SEQ ID NO:
- 547,
- wherein the second bacteria is selected from Clostridium oroticum or a bacterial species having a 16S rDNA sequence with at least 97% identity to SEQ ID NO:
- 610, and
- wherein the therapeutic composition comprises a lyophilized composition comprising the population of bacteria and microcrystalline cellulose.
Dependencies are inferred from the claim text.