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US 12,605,411 B2Granted
Phospholipid compositions for delivery of therapeutic compounds
AssigneeAker Biomarine Human Ingredients AS
InventorsThomas Beadnall, Finn Myhren, Nils Hoem
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Abstract
The present invention relates to compositions comprising phospholipids for delivery of bioactive compounds such as ethyl esters, fish oil concentrates, cannabinoids, CoQ10 and curcumin under conditions such the bioavailability of the bioactive compounds is enhanced.
Claims16
A lipid formulation for use in therapy by enhancing absorption of a therapeutic ingredient in a subject in need thereof, comprising:
- a) phospholipids from a marine source, wherein the phospholipids comprise more than 80% w/w phosphatidylcholine and wherein the molar content of omega-3 moieties in the phospholipids is more than 25%;
- and
- b) a therapeutic ingredient selected from the group consisting of a substance classified as class 2, 3 or 4 according to the Biopharmaceutical classification system (BCS) and a lipophilic substance from a source different from the marine source for the phospholipids;
- wherein the lipid formulation comprises more than 17% w/w of phospholipids and forms emulsions selected from the group consisting of emulsions with a droplet size of from 150 nm to 600 nm in an artificial stomach fluid determined through dynamic light scattering.
1 more element
Dependencies are inferred from the claim text.