Therapeutic uses of oxidizing hypotonic acid solutions
AssigneeAPR Applied Pharma Research S.A.
InventorsGiorgio Reiner, Paolo Galfetti, Roberto De Noni
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Abstract
Methods for treating or preventing ulcers caused by Epidermolysis Bullosa (“EB”), EGFR inhibitor-induced skin toxicities, lesions caused by Hailey-Hailey Disease (“HHD”), Buruli Ulcers, and SARS-CoV-2 infections, by topically applying a hypotonic, acid oxidizing solution containing hypochlorous acid (HClO) to the affected area.
Claims22
A method of treating a wound caused by Epidermolysis Bullosa (“EB”) in a patient in need thereof comprising topically applying to said wound a therapeutically effective amount of a hypotonic, acid oxidizing, aqueous solution comprising a pH of from 2.5 to 6, a chloride content of less than 400 mg/L, and a free chlorine content of 20-140 mg/L, wherein said free chlorine content comprises ≥90 w/w % of hypochlorous acid (HClO), ≤10 w/w % of chlorine (Cl2), and ≤3 w/w % of hypochlorite (ClO−).
Dependencies are inferred from the claim text.