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US 12,605,379 B2Granted
Methods of improving lung function
AssigneeEndeavor BioMedicines, Inc.
InventorsMiguel de los Rios, John Hood, Anita J. DiFrancesco, Luis A. Dellamary, Paul A. Frohna
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Abstract
The present disclosure provides methods of treating pulmonary fibrosis, the methods comprising administering taladegib to a subject in need thereof.
Claims29
A method of reversing pulmonary fibrosis, the method comprising administering taladegib, or a pharmaceutically acceptable salt thereof, to a subject suffering from or diagnosed with pulmonary fibrosis according to a treatment regimen that improves lung function in the subject, wherein the improvement in lung function comprises one or more of the following:
- an increase in total lung capacity (TLC) as compared to baseline TLC;
- a reduction in one or more measures of lung fibrosis;
- an increase in lung volume;
- or
- reducing pulmonary vascular volume.
2 more elements
Dependencies are inferred from the claim text.