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US 12,605,377 B2Granted
Methods of treating fibrosis
AssigneeEndeavor BioMedicines, Inc.
InventorsLuis A Dellamary, Sunil Kumar KC
Life of this patent
Estimating the term…
Abstract
The present specification provides methods and compositions for treating fibrosis, particularly pulmonary fibrosis. The pulmonary fibrosis may be idiopathic or arise following an infection of the lung. The lung infection can be by SARS-CoV-2. Lung function stabilizes or is improved as a result of treatment.
Claims15
A method of formulating a dry pharmaceutical composition comprising an active agent,
- wherein said active agent comprises a compound of Formula I:
- wherein,
- R1 is hydrogen or methyl;
- R2 is hydrogen or methyl;
- R3, R4, R5, R6, or R7 are independently hydrogen, fluoro, chloro, cyano, trifluoromethyl, trifluoromethoxy, difluoromethoxy, methylsulfonyl, or trifluoromethylsulfonyl,
- provided that at least three of R3, R4, R5, R6, and R7 are hydrogen;
- or a pharmaceutically acceptable salt thereof;
- the method comprising mixing the active agent with a polymer to form a solution or homogeneous mixture, and drying the mixture to obtain a solid or finely divided solid.
5 more elements
Dependencies are inferred from the claim text.