Compositions and methods using xanthan gum to stabilize at least one urolithin in an aqueous matrix
AssigneeSociete des Produits Nestle S.A.
InventorsAnupama Dattatreya, Vivek Dilip Savant, Loretta Grant, Sanjay Gupta
Life of this patent
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Abstract
A powder contains xanthan gum and at least one urolithin, such as Urolithin A; and the powder can be reconstituted in a liquid such as water to form a liquid composition for oral consumption, such as a beverage. The xanthan gum can keep the majority of the at least one urolithin in suspension in the beverage. The resultant liquid composition for oral consumption is another aspect of the present disclosure, as well as methods of making the powder, making the liquid composition for oral consumption, and using the powder or liquid composition prophylactically or therapeutically.
Claims13
A powder comprising xanthan gum and further comprising at least one compound of Formula (I) or a salt thereof:
- wherein A, B, C and D are each independently selected from H and OH;
- W, X and Y are each independently selected from H and OH;
- and Z is selected from H and OH.
A method of reducing risk and/or severity of or treating a disease or condition selected from the group consisting of metabolic syndrome, reduced metabolic rate, metabolic stress, cardiovascular disease, sarcopenia, muscle degenerative disease, Duchenne muscular dystrophy, alcoholic liver disease, nonalcoholic fatty liver disease, drug-induced liver injury, drug-induced cravings, anaemia disorders, al-antitrypsin deficiency, ischemia/reperfusion injury, inflammation, aging of the skin, inflammatory bowel disease, Crohn's disease, obesity, metabolic syndrome, type II diabetes mellitus, hyperlipidemia, osteoarthritis, neurodegenerative disease, Alzheimer's disease, Parkinson's disease, multiple sclerosis, anxiety disorder, ulceration, amyotrophic lateral sclerosis, age-related macular degeneration, cancer, cognitive disorder, stress, mood disorder, and combinations thereof, the method comprising:
- orally administering an effective amount of a beverage reconstituted from a powder comprising xanthan gum and further comprising at least one compound of Formula (I) or a salt thereof:
- wherein A, B, C and D are each independently selected from H and OH;
- W, X and Y are each independently selected from H and OH;
- and Z is selected from H and OH to a subject in need thereof having the disease or condition or at risk of the disease or condition.
A method of achieving at least one result selected from the group consisting of (i) managing body weight, (ii) promoting at least one of muscle performance or mental performance, (iii) maintaining at least one of muscle function, strength or stamina, (iv) reducing risk and/or severity of muscle decline with age, (v) maintaining or enhancing mitochondrial function (mitophagy), and (vi) supporting or promoting at least one of cellular renewal or cellular protection, the method comprising:
- orally administering an effective amount of a powder comprising xanthan gum and further comprising at least one compound of Formula (I) or a salt thereof:
- wherein A, B, C and D are each independently selected from H and OH;
- W, X and Y are each independently selected from H and OH;
- and Z is selected from H and OH to a subject in need thereof.
Dependencies are inferred from the claim text.