Composition for preventing or treating nervous system diseases comprising compound that inhibits mTOR signaling pathway as active ingredient
AssigneeAliad Biopharma
InventorsYunhee Kim, Hyockman Kwon, Young Taek Han
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Abstract
The present invention relates to a novel compound that inhibits the mTOR signaling pathway, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. The compound of the present invention was found to inhibit mTORC1 and mTORC2 activities, activate autophagy, and alleviate a series of disease symptoms associated with Alzheimer's-type dementia in dementia model animals, and thus can be effectively used as a pharmaceutical composition capable of preventing or treating nervous system diseases comprising neurodegenerative diseases and mTORopathy.
Claims9
A method for treating neurodegenerative disease, comprising administering a composition comprising 7,9-dimethoxy-10H-[1,3]dioxolo[4,5-b]xanthen-10-one, or a pharmaceutically acceptable salt thereof as an active ingredient to a subject in need thereof.
Dependencies are inferred from the claim text.