Methods of treating grade 3 astrocytoma
AssigneeOrbus Therapeutics, Inc.
InventorsJason D. Levin, Victor A. Levin, Noymi Yam
Life of this patent
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Abstract
Described herein are compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds for the treatment of conditions, diseases, or disorders, e.g., grade 3 astrocytoma.
Claims20
A method of treating glioma, comprising the steps of:
- (a) selecting a subject with mutant IDH and no homozygous deletion of CDKN2A/B genes;
- and
- (b) administering to said subject eflornithine or a salt thereof.
A method of treating glioma in a subject with mutant IDH gene and no homozygous deletion of CDKN2A/B genes, comprising administering to the subject eflornithine or a salt thereof.
A method of treating glioma in a subject, comprising screening for and selecting a subject with mutant IDH gene and no homozygous deletion of CDKN2A/B genes, and administering to the subject eflornithine or a salt thereof.
Dependencies are inferred from the claim text.