Polymer-encapsulated drug particles
AssigneeTonic Medical, Inc.
InventorsLixiao Wang, Peter Barnett
Life of this patent
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Abstract
Various embodiments disclosed relate to polymer-encapsulated drug particles and a drug-releasing coating including the same, as well as drug-coated balloon catheters for treating, preventing, or reducing the recurrence of strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes the polymer-encapsulated drug particles; or a drug-releasing coating including the polymer-encapsulated drug particles; or a therapeutic agent and a first and/or second additive; or a combination thereof.
Claims20
A method of reducing the occurrence of cancer, the method comprising:
- providing a balloon catheter into a target site in a body lumen, wherein the target site is at, proximate to, proximal to, or distal to a site of a performed cancer treatment, wherein the balloon catheter comprises
- an elongated balloon, and
- a coating layer overlying an exterior surface of the balloon, wherein the coating layer comprises one or more additives and an initial drug load of a therapeutic agent;
- inflating the balloon at the target site to contact the coating layer with walls of the body lumen at the target site;
- deflating the balloon;
- and
- removing the balloon catheter from the target site;
- wherein the body lumen is an esophagus, airway, sinus, trachea, colon, biliary tract, stomach, small intestine, duodenum, jejunum, ileum, rectum, or large intestine.
Dependencies are inferred from the claim text.