Medical device inserters and processes of inserting and using medical devices

An assembly for insertion of a transcutaneous glucose sensor in a continuous glucose monitoring system, the assembly comprising:

• a first housing comprising an exterior surface defining an outer button;
• a second housing slidably coupled with the first housing, wherein at least a portion of the second housing is disposed within an interior space of the first housing;
• a first spring disposed within the interior space of the first housing in between the first housing and the second housing, wherein the first spring is configured to compress in response to a predetermined force applied to the first housing;
• a plunger coupled with a sharp hub and an on-body unit configured to be worn on a body of a user, wherein the sharp hub is coupled with a sharp, and wherein the plunger comprises a plurality of distally-extended arms configured to engage the on-body unit;
• a second spring operatively coupled with the plunger, wherein the second spring is configured to advance the plunger, the sharp hub, the sharp, and the on-body unit from a proximal position to a distal position, wherein, in the distal position, the sharp is driven into skin and the on-body unit is adhered to the user;
• a third spring coupled with the plunger, wherein at least a portion of the plunger extends into an interior of the third spring, and wherein the third spring is configured to retract the sharp hub and the sharp from the distal position to a retracted position;
• the on-body unit, comprising:
• the transcutaneous glucose sensor, comprising:
• a proximal portion coupled with sensor electronics;
• and
• a distal portion configured to be positioned under the skin and in contact with interstitial fluid, wherein the distal portion of the transcutaneous glucose sensor is further configured to detect a glucose level of the user;
• the sensor electronics, comprising:
• a power supply;
• wireless communication circuitry configured to transmit data indicative of the glucose level according to a wireless communication protocol;
• and
• processing circuitry coupled with a memory,
• wherein the on-body unit further comprises an aperture disposed on a top surface, and wherein, in the proximal position, the sharp hub is maintained on the top surface of the on-body unit with the sharp extending through the aperture of the on-body unit.