Medical device inserters and processes of inserting and using medical devices

An inserter assembly for partially inserting a glucose sensor into a subject, the inserter assembly comprising:

• an inserter housing;
• an actuator button;
• a carrier coupled with a sharp, the sharp configured to be inserted into a skin of the subject;
• the glucose sensor releasably coupled with the sharp, the glucose sensor comprising:
• a distal portion configured to be positioned under the skin of the subject and in contact with an interstitial fluid of the subject, and
• a proximal portion configured to be positioned above the skin and coupled with sensor electronics;
• an elastomeric retention member disposed within the inserter housing, wherein the elastomeric retention member is a separate structure from the glucose sensor, the carrier, and the sharp, and wherein the elastomeric retention member is not integral with any of the glucose sensor, the carrier, or the sharp;
• a drive spring configured to, upon depression of the actuator button, advance the carrier, the sharp, and the glucose sensor from a proximal position to a distal position;
• and
• a retraction spring configured to retract the carrier and the sharp from the distal position to a retracted position entirely within the inserter housing,
• wherein the elastomeric retention member is configured to retain a part of the glucose sensor within the sharp while the carrier, the sharp, and the glucose sensor are in the proximal position, and
• wherein the glucose sensor is configured to have a predetermined monitoring time period of fourteen days.