# US 12,601,931 B2 · Photo-biomodulation by endogenous auto-fluorescent compounds

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- Number: US 12,601,931 B2
- Document ID: US12601931B2
- Status: Granted
- Kind: B2
- Application number: 16/627,281
- Filed: 2018-01-30
- Published: 2020-04-30
- Granted: 2026-04-14
- Earliest claimed: 2013-07-12
- Assignees: Photoprotective Technologies Incorporated
- Applicants: Photoprotective Technologies Incorporated
- Inventors: James M. Gallas; Matthew T. Gordon
- Web page: https://patentgrep.com/patent/US12601931B2

## CPC

- G02C 7/104: {having spectral characteristics for purposes other than sun-protection}
- G02B 5/208: {for use with infrared or ultraviolet radiation, e.g. for separating visible light from infrared and/or ultraviolet radiation}
- G02B 5/223: {containing organic substances, e.g. dyes, inks or pigments}
- G02C 7/108: {Colouring materials}
- G02C: SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES (trial frames for testing the eyes A61B3/04; goggles or eyeshields not having the same features as spectacles A61F9/00)
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS

## Abstract

According to the present invention, light filters are disclosed that provide photoprotection and contain fluorescent agents in that have fluorescence emission in the near infrared region of wavelengths to effect photobiological modulation (PBM) of human cells when the cells are exposed to sunlight or any artificial lighting. The fluorescent agents include endogenous compounds. The light filters include ophthalmic lenses, skin care products with or without transparent substrate and any products that are used to filter light. When used in connection with ophthalmic lenses, the ophthalmic lense provides photoprotection and photobiological modulation to the human eye.

## Claims

### Claim 1

A light filter comprising:
a luminescent dye that is a synthetic version of a lipofuscin, an endogenous, naturally-occurring, compound found in the cells and tissue of humans that has a red and near infrared luminescence within the wavelength range from 600 nm to 1200; and
a transparent substrate which is a skin care product.