Contact lens
AssigneeCooperVision International Limited
InventorsErwin C. Si, Nancy J. Keir, Yuwen Liu, Inna Maltseva
Life of this patent
Estimating the term…
Abstract
A contact lens having an amount of at least one cooling agent and at least one TRPV1 inhibitor releasably adhered is described as well as method of manufacturing the same. The contact lens can be comfortably worn by contact lens wearers and can increase the duration of comfortable lens wearing time and/or reduce lens awareness events and/or reduce contact lens dryness in a symptomatic contact lens wearer and further can reduce or avoid any stinging/burning sensation when the contact lens is first used or a short time thereafter.
Claims32
An unworn sterile hydrogel contact lens immersed in a packaging solution and sealed in a package, said contact lens comprising:
- a) a polymeric lens body;
- b) an amount of a cooling agent releasably adhered to the polymeric lens body;
- and
- c) an amount of a TRPV1 inhibitor either releasably adhered to the polymeric lens body or present in the packaging solution or both, wherein the TRPV1 inhibitor has a first in vitro release profile and the cooling agent has a second in vitro release profile, and the first release profile is faster than the second release profile, based on percent of total loaded amount of the TRPV1 inhibitor and the cooling agent released in an initial 1 to 3 hours of release.
Dependencies are inferred from the claim text.