Sensor
AssigneeSensocure AS
InventorStein Ivar Hansen
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Abstract
The invention provides a physiological sensing device for the measurement of pCO2, the device comprising: (i) a closed chamber bounded, at least partially, by a carbon dioxide permeable membrane; and (ii) at least two electrodes within said chamber, wherein said chamber contains a substantially electrolyte-free liquid in contact with the electrodes and the membrane and wherein the liquid comprises at least one metal or metalloid ion.
Claims20
A physiological sensing device for a measurement of pCO2, the sensing device comprising:
- (i) a closed chamber bounded, at least partially, by a carbon dioxide permeable membrane;
- and
- (ii) at least two electrodes within said chamber,
- wherein said chamber contains a substantially electrolyte-free liquid in contact with the at least two electrodes and the membrane and wherein the liquid comprises at least one metal or metalloid ion, wherein the at least one metal or metalloid ion comprises Cu, and wherein if the at least one metal or metalloid ion is provided in a form of a metal complex comprising ligands, then the ligands are selected from carbon monoxide, carbon dioxide, water, nitrite and ammonia;
- and
- wherein the substantially electrolyte-free liquid has an ionic osmolality no greater than that at 37° C. of an aqueous 5 mM sodium chloride solution.
A method for measuring pCO2, said method comprising a step of measuring a change in conductivity of a substantially electrolyte-free liquid in a presence of CO2, wherein said liquid comprises at least one metal or metalloid ion, wherein the at least one metal or metalloid ion comprises Cu, and wherein if the at least one metal or metalloid ion is provided in the form of a metal complex comprising ligands, then the ligands are selected from carbon monoxide, carbon dioxide, water, nitrite and ammonia;
- and wherein the substantially electrolyte-free liquid has an ionic osmolality no greater than that at 37° C. of an aqueous 5 mM sodium chloride solution.
A method for amplifying a change in conductivity of a substantially electrolyte-free liquid in a presence of CO2, said method comprising adding at least one metal or metalloid ion to said liquid, wherein the at least one metal or metalloid ion comprises Cu, and wherein if the at least one metal or metalloid ion is provided in a form of a metal complex comprising ligands, then the ligands are selected from carbon monoxide, carbon dioxide, water, nitrite and ammonia;
- and wherein the substantially electrolyte-free liquid has an ionic osmolality no greater than that at 37° C. of an aqueous 5 mM sodium chloride solution.
Dependencies are inferred from the claim text.