Rapid diagnostics for analyte/biomarker detection by Raman technology with non-spectrometer Raman measurement system

A portable device which detects a Raman signal from an analyte of interest contained in or suspected to contain in a sample, the portable device comprising:

• a laser source in optical communication with a dichroic mirror;
• an objective lens optically positioned to consolidate the laser beam from the laser source to the sample;
• (i) a pair of rotatable filters in optical communication with the dichroic mirror and an optical transmission module, or (ii) a first band-pass filter in optical communication with the dichroic mirror and an optical transmission module, wherein the first band-pass filter is tunable;
• a rotational member operably connected to the pair of rotatable filters or the first band-pass filter;
• and
• a detector optically positioned to receive and detect a Raman signal produced from the laser beam incident on the analyte of interest,
• wherein the dichroic mirror directs the laser beam from the laser source to the sample through the objective lens and transmits any Raman signal from the sample toward the detector,
• wherein the dichroic mirror is optically pervious to any Raman signal having a wavelength longer than the wavelength of the laser beam from the laser source, and
• wherein the detector is absent of a spectrometer and remains operable to detect the Raman signal.