Compounds and methods targeting epiregulin
AssigneeEli Lilly and Company
InventorsCatherine Brautigam Beidler, Jeffrey Streetman Boyles, Daniel Scott Girard, Shannon Marie Harlan, Michael Parvin Johnson
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Abstract
The present invention relates to epiregulin antibodies, compositions comprising the same, and methods of making and/or using the antibodies and/or compositions thereof for chronic pain disorders such as chronic osteoarthritis pain, or chronic diabetic peripheral neuropathy pain, or chronic low back pain.
Claims4
An antibody that binds human epiregulin wherein the antibody comprises a heavy chain variable region (VH) and a light chain variable region (VL), wherein the VH comprises heavy chain complementarity determining regions (HCDR) HCDR1, HCDR2, and HCDR3, and the VL comprises light chain complementarity determining regions (LCDR) LCDR1, LCDR2, and LCDR3, wherein
- the HCDR1 comprises SEQ ID NO:
- 5,
- the HCDR2 comprises SEQ ID NO:
- 6,
- the HCDR3 comprises SEQ ID NO:
- 7,
- the LCDR1 comprises SEQ ID NO:
- 8,
- the LCDR2 comprises SEQ ID NO:
- 9, and
- the LCDR3 comprises SEQ ID NO:
- 10.
Dependencies are inferred from the claim text.