# US 12,599,781 B2 · Assessing treatment parameters for radiation treatment planning

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- Number: US 12,599,781 B2
- Document ID: US12599781B2
- Status: Granted
- Kind: B2
- Application number: 18/108,539
- Filed: 2023-02-10
- Published: 2023-06-22
- Granted: 2026-04-14
- Earliest claimed: 2021-06-29
- Assignees: Siemens Healthineers International AG
- Applicants: Siemens Healthineers International
- Inventors: Viljo Petaja; Anthony Magliari; Pierre Lansonneur; Jessica Perez; Michiko Rossi; Michael Folkerts
- Web page: https://patentgrep.com/patent/US12599781B2

## CPC

- A61N 5/103: {Treatment planning systems}
- A61N 5/1031: {using a specific method of dose optimization}
- A61N 5/1045: {using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT}
- A61N 5/1048: {Monitoring, verifying, controlling systems and methods}
- G16H 10/60: for patient-specific data, e.g. for electronic patient records
- G16H 20/40: relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
- G16H 30/40: for processing medical images, e.g. editing
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- G16H 50/50: for simulation or modelling of medical disorders
- G16H 70/20: relating to practices or guidelines
- A61N 2005/1074: {Details of the control system, e.g. user interfaces}
- A61N 2005/1087: {Ions; Protons}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

Information associated with a radiation treatment plan includes, for example, values of dose per voxel in a target volume, values of dose rate per voxel in the target volume, and values of parameters used when generating the values of dose per voxel and the values of dose rate per voxel. Renderings that include, for example, a rendering of an image of or including the target volume, and a rendering of selected values of the radiation treatment plan, are displayed. When a selection of a region of one of the renderings is received, a displayed characteristic of another one of the renderings is changed based on the selection.

## Claims

### Claim 1

One or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by a computer system, cause the computer system to perform a radiation treatment planning method comprising:
displaying, on a display device of the computer system, a first rendering and a second rendering, wherein the first rendering includes an image of a target volume using a first display characteristic, and wherein the second rendering represents at least a portion of the target volume and includes parameter values of a radiation treatment plan for the target volume using a second display characteristic; and
in response to receiving an input including a selection of a sub-region of a given one of the first rendering or the second rendering, changing the given one of the first display characteristic or the second display characteristic of a corresponding sub-region of another one of the first rendering or the second rendering,
wherein the second rendering includes a rendering showing locations in the target volume intersected by a given beam segment or field in a beams-eye view.

### Claim 2 (depends on 1)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 1, wherein the locations in the second rendering are locations where the given beam segment or field delivers more than a threshold amount of dose.

### Claim 3 (depends on 1)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 1, wherein the locations in the second rendering are locations where the given beam segment or field delivers more than a threshold dose rate.

### Claim 4 (depends on 1)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 1, wherein the parameter values of the radiation treatment plan include one or more of dose per voxel in a target volume, dose rate per voxel in the target volume, or relative biological effectiveness (RBE) per voxel.

### Claim 5 (depends on 1)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 1, wherein the first display characteristic and the second display characteristic are selected from a group including:
color;
pattern;
grayscale;
alphanumeric text; and
brightness.

### Claim 6

A computer system comprising:
a processor;
a display device coupled to the processor; and
a memory coupled to the processor, the memory storing instructions that, when executed by the processor, cause the computer system to:
display, on the display device of the computer system, a first rendering and a second rendering, wherein the first rendering includes an image of a target volume using a first display characteristic, and wherein the second rendering represents at least a portion of the target volume and includes parameter values of a radiation treatment plan for the target volume using a second display characteristic; and
in response to receiving an input including a selection of a sub-region of a given one of the first rendering or the second rendering, change the given one of the first display characteristic or the second display characteristic of a corresponding sub-region of another one of the first rendering or the second rendering,
wherein the second rendering includes a rendering showing locations in the target volume intersected by a given beam segment or field in a beams-eye view.

### Claim 7 (depends on 6)

The computer system of claim 6, wherein the locations in the second rendering are locations where the given beam segments or field delivers more than a threshold amount of dose.

### Claim 8 (depends on 6)

The computer system of claim 6, wherein the locations in the second rendering are locations where the given beam segment or field delivers more than a threshold dose rate.

### Claim 9 (depends on 6)

The computer system of claim 6, wherein the parameter values of the radiation treatment plan include one or more of dose per voxel in a target volume, dose rate per voxel in the target volume, or relative biological effectiveness (RBE) per voxel.

### Claim 10 (depends on 6)

The computer system of claim 6, wherein the first display characteristic and the second display characteristic are selected from a group including:
color;
pattern;
grayscale;
alphanumeric text; and
brightness.

### Claim 11

One or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by a computer system, cause the computer system to perform a radiation treatment planning method comprising:
displaying, on a display device of the computer system, a first rendering and a second rendering, wherein the first rendering includes an image of a target volume using a first display characteristic, and wherein the second rendering represents at least a portion of the target volume and includes parameter values of a radiation treatment plan for the target volume using a second display characteristic; and
in response to receiving an input including a selection of a sub-region of a given one of the first rendering or the second rendering, changing the given one of the first display characteristic or the second display characteristic of a corresponding sub-region of another one of the first rendering or the second rendering,
wherein the second rendering includes a dose-dose rate scatter plot with voxels in the dose-dose rate scatter plot being voxels intersected by more than a threshold number of beams of radiation.

### Claim 12 (depends on 11)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 11, wherein the parameter values of the radiation treatment plan include one or more of dose per voxel in a target volume, dose rate per voxel in the target volume, or relative biological effectiveness (RBE) per voxel.

### Claim 13 (depends on 11)

The one or more non-transitory computer-readable storage medium storing computer-executable instruction that, when executed by the computer system, cause the computer system to perform the radiation treatment planning method according to claim 11, wherein the first display characteristic and the second display characteristic are selected from a group including:
color;
pattern;
grayscale;
alphanumeric text; and
brightness.

### Claim 14

A computer system comprising:
a processor;
a display device coupled to the processor; and
a memory coupled to the processor, the memory storing instructions that, when executed by the processor, cause the computer system to
display, on the display device, a first rendering and a second rendering, wherein the first rendering includes an image of a target volume using a first display characteristic, and wherein the second rendering represents at least a portion of the target volume and includes parameter values of a radiation treatment plan for the target volume using a second display characteristic, and
in response to receiving an input including a selection of a sub-region of a given one of the first rendering or the second rendering, changing the given one of the first display characteristic or the second display characteristic of a corresponding sub-region of another one of the first rendering or the second rendering,
wherein the second rendering includes a dose-dose rate scatter plot with voxels in the dose-dose rate scatter plot being voxels intersected by more than a threshold number of beams of radiation.

### Claim 15 (depends on 14)

The computer system of claim 14, wherein the parameter values of the radiation treatment plan include one or more of dose per voxel in a target volume, dose rate per voxel in the target volume, or relative biological effectiveness (RBE) per voxel.

### Claim 16 (depends on 14)

The computer system of claim 14, wherein the first display characteristic and the second display characteristic are selected from a group including:
color;
pattern;
grayscale;
alphanumeric text; and
brightness.