# US 12,599,769 B2 · Balloon-type retinal stimulation device and method for manufacturing same > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,599,769 B2 - Document ID: US12599769B2 - Status: Granted - Kind: B2 - Application number: 18/367,566 - Filed: 2023-09-13 - Published: 2024-01-04 - Granted: 2026-04-14 - Earliest claimed: 2017-12-06 - Assignees: Daegu Gyeongbuk Institute of Science and Technology - Applicants: Daegu Gyeongbuk Institute of Science and Technology - Inventors: So Hee Kim; Hyun Min Moon; Nam Sun Chou - Web page: https://patentgrep.com/patent/US12599769B2 ## CPC - A61N 1/36046: {of the eye} - A61B 5/24: Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof - A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)} - A61N 1/0543: {Retinal electrodes} - A61N 1/08: Arrangements or circuits for monitoring, protecting, controlling or indicating {(for external stimulators A61N1/3603; for implantable neurostimulators A61N1/36128; for heart stimulators A61N1/37; for defibrillators A61N1/3925)} - H01B 5/14: comprising conductive layers or films on insulating-supports - A61F 2240/001: Designing or manufacturing processes - A61F 2250/0003: having an inflatable pocket filled with fluid, e.g. liquid or gas - A61F 2250/0013: for adjusting fluid pressure - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - H01B: CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES (selection for magnetic properties H01F1/00; waveguides H01P {; printed circuits H05K}) ## Abstract A balloon type retinal stimulation device includes: a substrate unit having an insertion portion provided to be inserted into an eyeball; and a stimulation unit that is provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is provided to be expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion is deformed to match a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed. ## Claims ### Claim 1 A method for manufacturing a balloon type retinal stimulation device, comprising: a) a step of preparing a lower substrate and an upper substrate; b) a step of performing adhesion of the prepared upper substrate and lower substrate; c) a step of forming a metal electrode layer over the adhesion-performed upper substrate; and d) a step of forming an insulation layer on the metal electrode layer, wherein, in the step a), the lower substrate is provided to be prepared by forming a first spin-coated polydimethylsiloxane (PDMS) layer over a carrier substrate and forming a first Parylene layer by applying Parylene over the first spin-coated PDMS layer, and the upper substrate is provided to be prepared by forming a second spin-coated PDMS layer over the first Parylene layer. ### Claim 2 (depends on 1) The method for manufacturing a balloon type retinal stimulation device according to claim 1, wherein the step b) includes: b1) a step of forming first masking patterns over the prepared upper substrate; b2) a step of irradiating the first masking patterns with plasma; and b3) a step of removing the first masking patterns. ### Claim 3 (depends on 2) The method for manufacturing a balloon type retinal stimulation device according to claim 2, wherein, in the step b1), the first masking patterns are formed at sites where the upper substrate and the lower substrate are bonded to each other. ### Claim 4 (depends on 2) The method for manufacturing a balloon type retinal stimulation device according to claim 2, wherein, in the step b2), the plasma with which irradiation is performed to the first masking patterns causes the first Parylene layer positioned at an outer side of the first masking patterns to adhere to the upper substrate. ### Claim 5 (depends on 2) The method for manufacturing a balloon type retinal stimulation device according to claim 2, wherein the step c) includes: c1) a step of forming a second Parylene layer by applying Parylene over the upper substrate; c2) a step of forming a metal thin-film layer by applying a metal thin-film over the second Parylene layer; c3) a step of forming second masking patterns over the applied metal thin-film layer; c4) a step of forming the metal electrode layer by patterning the metal thin-film layer by using the second masking patterns; and c5) a step of removing the second masking patterns. ### Claim 6 (depends on 5) The method for manufacturing a balloon type retinal stimulation device according to claim 5, wherein, in the step c4), the metal thin-film layer is provided to be patterned into a preset pattern by performing a wet etching process according to pattern shapes of the second masking patterns. ### Claim 7 (depends on 5) The method for manufacturing a balloon type retinal stimulation device according to claim 5, wherein, in the step c4), the metal thin-film layer is provided to be patterned into a preset pattern by performing a lift-off process according to pattern shapes of the second masking patterns. ### Claim 8 (depends on 5) The method for manufacturing a balloon type retinal stimulation device according to claim 5, wherein the step d) includes: d1) a step of forming a third Parylene layer by applying Parylene on the metal electrode layer; d2) a step of forming third masking patterns over the third Parylene layer; d3) a step of forming the insulation layer by irradiating the third masking patterns with plasma and etching the third Parylene layer according to pattern shapes of the third masking patterns; and d4) a step of removing the third masking patterns. ### Claim 9 (depends on 8) The method for manufacturing a balloon type retinal stimulation device according to claim 8, wherein, in the step c3), the third masking patterns are irradiated with O2 plasma. ### Claim 10 (depends on 1) The method for manufacturing a balloon type retinal stimulation device according to claim 1, further comprising: e) a step of removing a carrier substrate included in the lower substrate after the step d).