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US 12,599,700 B2Granted
System and methods for connective tissue repair using scaffolds
AssigneeChildren's Medical Center Corporation
InventorMartha M. Murray
Life of this patent
Estimating the term…
Abstract
Methods and devices for repair of a torn or ruptured ligament using a scaffold device are provided. Aspects of the present disclosure include method of placement and fixation of sutures using a fixation device. In aspects of the present disclosure, the method includes notchplasty and delayed rehabilitation.
Claims40
A method for repairing a tear of an anterior cruciate ligament (ACL), comprising:
- contacting a torn femoral stump of the ACL and a torn tibial stump of the ACL with a compressible and expandable scaffold comprised of a self-assembly of enzyme-solubilized collagen fibers comprising tropocollagen or atelocollagen, the scaffold having a collagen concentration of at least 10 mg/mL,
- wherein the torn tibial stump has a tibial stump length that is less than 75% but greater than 5% of a total length of the ACL, and
- wherein the scaffold is hydrophilic and free of cross links, and
- wherein the content of nucleic acids in the collagen material is less than 20% of that found in a native tissue.
1 more element
A method for repairing a tear of an anterior cruciate ligament (ACL), comprising:
- performing a notchplasty to a femur such that a larger ACL is formed after repair;
- and
- contacting a torn femoral stump of the ACL and a torn tibial stump of the ACL with a compressible and expandable scaffold comprised of a self-assembly of enzyme-solubilized collagen fibers comprising tropocollagen and atelocollagen, the scaffold having a collagen concentration of at least 10 mg/mL;
- and
- adding a repair material to the scaffold,
- wherein the scaffold is hydrophilic and free of cross links, and
- wherein the content of nucleic acids in the collagen fibers is less than 20% of that found in a native tissue.
4 more elements
Dependencies are inferred from the claim text.