Augmented thermoset polymer sponges for in situ hemostatic treatment of external and internal wounds

A portable hemostatic bandage system comprising two formulations to form a polymer foam as in situ wound dressing at ambient temperatures for the control of mild, moderate, and severe hemorrhage, the portable hemostatic bandage system comprising:

• i) a first formulation comprising at least one type of polymer, at least one surfactant, at least one inorganic oxide or organic oxide or organic anhydride, and at least one polymer curing catalyst, wherein the at least one type of polymer in the first formulation comprises poly(dimethylsiloxane) (PDMS) and poly(dimethylsiloxane)-poly(ethylene oxide (PDMS-PEO);
• ii) a second formulation comprising at least one type of polymer at least one surfactant, hydrogen peroxide, and optionally, an aggregate;
• and
• ii) a dual container device having two separate chambers for keeping the two formulations separately, mixing the two formulations, and applying the resultant sponge-like polymer foam to the bleeding wound;
• wherein the polymer(s) in the second formulation can be at least one selected from siloxanes, functional siloxanes, vinyl terminated polymers, polyurethanes, polyacrylates, polymethylmethacrylates, epoxies, copolymers thereof, or mixture thereof,
• wherein the polymer(s) in the first and second formulations can be the same type of polymer or polymer mixture, or the polymer or the polymer mixture in the first formulation can be different from the polymer or polymer mixture in the second formulation, and
• wherein the first and second formulations are sterilized before packed into the separate chambers of the dual container device.