Compositions and treatments for ischemic injuries
AssigneeUniversity of Utah Research Foundation
InventorsHadi Javan, Craig H. Selzman, Young Sook Lee, Jo-Anna Reems, Jan L. Pierce
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Abstract
Described herein are compositions and methods for treating ischemic injury in a subject comprising administering a therapeutically effective amount of an acellular amniotic fluid (acAF) to an ischemic injury situs within a therapeutic time window.
Claims31
A method of treating an ischemic injury in a subject, comprising:
- locally injecting a therapeutically effective amount of an acellular amniotic fluid (acAF) to an ischemic injury situs within a therapeutic time window.
A method of treating a cardiac ischemic event in a subject, comprising:
- locally injecting a therapeutically effective amount of acellular amniotic fluid (acAF) to an ischemic situs of a heart of the subject within a therapeutic time window.
A method of treating fibrosis in a subject, comprising:
- locally injecting a therapeutically effective amount of acellular amniotic fluid (acAF) to an ischemic situs of the subject within a therapeutic time window.
A method of treating peripheral arterial disease (PAD) in a subject, comprising:
- locally injecting a therapeutically effective amount of acellular amniotic fluid (acAF) to an ischemic situs of a lower extremity of the subject within a therapeutic time window.
A method of treating cyanosis in a subject, comprising:
- locally injecting a therapeutically effective amount of acellular amniotic fluid (acAF) to an ischemic situs of an extremity of the subject, wherein the therapeutically effective amount is administered via a dosage regimen.
Dependencies are inferred from the claim text.