Method of deploying an intraluminal device and intraluminal system

A method of deploying an intraluminal device to the cardiac region of the stomach, the device comprising a wall defining a surface and an open portion said wall that is alignable with the gastroesophageal (GE) junction, said surface and the cardiac portion of the stomach conformable with each other, said method comprising:

• deploying the intraluminal device trans-orally to the stomach;
• retaining the intraluminal device in the stomach in contact with the cardiac portion of the stomach with the open portion generally aligned with the GE junction;
• fastening the retained intraluminal device to the cardiac portion of the stomach through a wall of the stomach from within the abdominal cavity with at least one laparoscopic instrument;
• visualizing the intraluminal device within the stomach with an endoscope during the fastening, wherein said fastening comprises suturing with suture strands and reinforcing the suture strands at the abdominal side of each suture strand wherein said reinforcing comprises producing scar material in the stomach tissue contacted by the suture strand;
• and
• explanting the intraluminal device by severing the suture strands in the stomach and pulling the knots of the severed suture strands through the stomach wall into the stomach.