# US 12,599,375 B2 · Medical material

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 12,599,375 B2
- Document ID: US12599375B2
- Status: Granted
- Kind: B2
- Application number: 18/686,726
- Filed: 2022-08-22
- Published: 2025-01-23
- Granted: 2026-04-14
- Earliest claimed: 2021-08-27
- Assignees: Gunze Limited
- Applicants: Gunze Limited
- Inventors: Yuuki Kato; Hinami Nakamura
- Web page: https://patentgrep.com/patent/US12599375B2

## CPC

- A61B 17/0057: {Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009)}
- A61B 17/00: Surgical instruments, devices or methods (A61B18/00 takes precedence; dental tools A61C3/00; eye surgery A61F9/007; ear surgery A61F11/20)
- A61B 2017/00004: {(bio)absorbable, (bio)resorbable or resorptive}
- A61B 2017/00575: {for closure at remote site, e.g. closing atrial septum defects}
- A61B 2017/00597: {Implements comprising a membrane}
- A61B 2017/00601: {Implements entirely comprised between the two sides of the opening}
- A61B 2017/00606: {Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening}
- A61B 2017/00619: {Locking means for locking the implement in expanded state}
- A61B 2017/00623: {Introducing or retrieving devices therefor}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A medical material makes it possible to perform less invasive treatment of atrial septal defect and is unlikely to cause problems in the late post-treatment period. A medical material includes a substantially middle portion and two tubular portions (first tubular portion, second tubular portion) having a mesh structure formed of a bioabsorbable linear material and includes a proximal connecting part connected to a first end and a distal connecting part connected to a second end and threaded to a delivery cable. The proximal connecting part and the distal connecting part are configured to reversibly or irreversibly achieve a locked state and an unlocked state, the locked state being a state in which the proximal connecting part and the distal connecting part remain united, the unlocked state being a state in which the proximal connecting part and the distal connecting part do not remain united. When the distal connecting part is inserted into the proximal connecting part, the engaging portion of the distal connecting part engages with the engaged portion of the proximal connecting part to cause the medical material to transition from the unlocked state to the locked state.

## Claims

### Claim 1

A medical material comprising a tubular body having a mesh structure formed of a bioabsorbable linear material and including a substantially middle portion and two tubular portions, the two tubular portions including a first tubular portion and a second tubular portion between which the substantially middle portion is provided; wherein
the substantially middle portion is smaller in tube diameter than other portions;
the first tubular portion with a first end and the second tubular portion with a second end are arranged with the substantially middle portion therebetween, the first end and the second end being opposite ends in a longitudinal direction of the tubular body;
when the medical material is contained in a catheter such that the first end and the second end are away from each other with the substantially middle portion therebetween and that the other portions have a reduced tube diameter, the second end is located on the same side of the catheter as a distal end of the catheter;
the medical material includes:
a proximal connecting part connected to the mesh structure at the first end; and
a distal connecting part connected to the mesh structure at the second end;
the proximal connecting part is substantially in a shape of a hollow cylinder, the distal connecting part is substantially in a shape of a cylinder, the proximal connecting part and the distal connecting part are configured such that the cylinder of the distal connecting part is insertable into the hollow cylinder of the proximal connecting part, and are configured to reversibly or irreversibly achieve a locked state and an unlocked state, the locked state being a state in which the proximal connecting part and the distal connecting part remain united, the unlocked state being a state in which the proximal connecting part and the distal connecting part do not remain united;
an inner diameter of the proximal connecting part is larger than an outer diameter of a delivery cable to be inserted into the catheter;
the distal connecting part is configured to selectively achieve a connected state in which the distal connecting part is connected to a distal end of the delivery cable and a disconnected state in which the distal connecting part is not connected to the distal end of the delivery cable;
the medical material is configured to allow the delivery cable, which has the distal end thereof connected to the distal connecting part, to extend through the substantially middle portion, be inserted into the hollow cylinder of the proximal connecting part, and extend out of the medical material in a direction from the second end to the first end;
the distal connecting part includes:
a radially outer portion larger than an outer diameter of the delivery cable and smaller than the inner diameter of the proximal connecting part; and
an engaging portion larger than an outer diameter of the radially outer portion;
the proximal connecting part includes:
a radially inner portion which fits the radially outer portion; and
an engaged portion which is larger than an inner diameter of the radially inner portion and which fits the engaging portion;
when the distal connecting part is inserted into the proximal connecting part, the engaging portion of the distal connecting part engages with the engaged portion of the proximal connecting part to cause a transition from the unlocked state to the locked state;
the medical material includes the delivery cable;
the proximal connecting part has expandability such that the inner diameter of a portion closer to the distal connecting part than the other portion of the proximal connecting part expands when the engaging portion is inserted into the radially inner portion and that the expanded inner diameter is de-expanded when the engaging portion engages with the engaged portion; and
the proximal connecting part, which is substantially in the shape of the hollow cylinder, achieves the expandability thereof by having four grooves which are spaced substantially 90 degrees apart from each other, which connect outer and inner surfaces of the hollow cylinder, and each of which extends along a longitudinal direction of the delivery cable from an end face facing the distal connecting part to a predetermined location short of an end face at the first end.